Software Package for GRASS Algorithm and Three Alternative Algorithms
The SNPath package contains algorithms for evaluating the association
between disease risk and a set of SNPs that belongs to the same functional gene set or
pathways. The package includes the newly developed regularized approach GRASS
(Chen et al. 2010) and three alternative algorithms in the literature: Wang et al.
(2007), PLINK set options (Purcell et al. 2007) and ALIGATOR (Holmans et al. 2009).
The SNPath package can be downloaded:
Chen LS, Hutter CM, Potter JD, Liu Y, Prentice RL, Peters U and Hsu L. (2010)
Insights into colon cancer etiology using a regularized approach to gene set analysis
of GWAS data. The American Journal of Human Genetics, 86(6): 860-871.
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